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DRCR Protocol V in the real world - retina-specialist.com
Protocol V aimed to answer one such question: How should we manage patients with good vision despite center-involving DME on exam and OCT? Based on the results of Protocol V, clinicians should feel more confident if they decide to observe these patients while following them closely.
DRCR PROTOCOL V - VBS Academy - Vit Buckle Society -
Protocol V was a double-blind, randomized clinical trial enrolling Type 1 or Type 2 diabetic eyes with central involving macular edema and good vision (20/25 or better)
Protocol V: Treatments show little difference for DME eyes with >20/25 VA
Effect of initial management with aflibercept vs laser photocoagulation vs observation on vision loss among patients with diabetic macular edema involving the center of the macula and good visual acuity: A randomized clinical trial.
Diabetic Macular Edema: Diagnosis and Management
In the DRCR.net Protocol V study, the investigators compared aflibercept, laser photocoagulation, and observation in the initial management of patients with center-involving DME and a baseline BCVA of 20/25 or better.
Management of patients with diabetic macular oedema and good visual ...
Management of patients with diabetic macular oedema and good visual acuity: new findings from Protocol V
Putting Protocol V Into Practice for Patients With DME
Protocol V was designed to provide guidance about treatment options for patients like this with edema and good vision. Image courtesy of Retinal Consultants of Texas. Protocol V provides results that apply to some, but not all, patients with diabetes.
Top Takeaways from DRCR Retina Network Protocol V
In the trial, patients with diabetic macular edema, well-controlled diabetes and good vision were treated using 3 strategies: aflibercept, observation with deferred aflibercept and focal photocoagulation. There were no significant difference in vision between the 3 groups at 2 years.
Managing Eyes with Center-Involved Diabetic Macular Edema and Good ...
Participants were adults with type 1 or 2 diabetes with one study eye having CI-DME and good VA randomly assigned to initial observation. Eyes were carefully followed and given aflibercept if VA decreased by 10 or more letters from baseline at any time or 5 to 9 letters at 2 consecutive visits.
Costs of Managing Diabetic Macular Edema with Good Visual Acuity with ...
Graphical Abstract Similar visual acuity outcomes on average are obtained by initially managing center-involved diabetic macular edema and good baseline visual acuity with laser or observation strategies instead of immediately using aflibercept.
Thresholds for Initiating Treatment of Eyes with Diabetic Macular Edema ...
Thresholds for Initiating Treatment of Eyes with Diabetic Macular Edema and Good Vision: Consideration of DRCR.Net Protocol V Results
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